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2010-2015

Great discovers come from great teams...

LINKAGE OF DNA METHYLATION QUANTITATIVE TRAIT LOCI TO HUMAN CANCER RISK (2014)

Holger Heyn, Sergi Sayols, Catia Moutinho, et al.

Cell Rep. 2014 Apr 24;7(2):331-338.
doi: 10.1016/j.celrep.2014.03.016. Epub 2014 Apr 3.

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A DERL3-ASSOCIATED DEFECT IN THE DEGRADATION OF SLC2A1 MEDIATES THE WARBURG EFFECT (2014)

Paula Lopez-Serra, Miguel Marcilla, Alberto Villanueva, et al.

Nat Commun. 2014 Apr 3;5:3608.

 doi: 10.1038/ncomms4608. CORRIGENDUM 2016

THE PDGFRΒ-AKT PATHWAY CONTRIBUTES TO CDDP-ACQUIRED RESISTANCE IN TESTICULAR GERM CELL TUMORS (2014)

M Juliachs, C Muñoz, C A Moutinho, et al.

Clin Cancer Res​. 2014 Feb 1;20(3):658-67.

 doi: 10.1158/1078-0432.CCR-13-1131. Epub 2013 Nov 25.

EPIGENETIC INACTIVATION OF THE BRCA1 INTERACTOR SRBC AND RESISTANCE TO OXALIPLATIN IN COLORECTAL CANCER (2014)

Catia Moutinho, Anna Martinez-Cardús, Cristina Santos, et al.

J Natl Cancer Inst. 2014 Jan;106(1):djt322.

 doi: 10.1093/jnci/djt322. Epub 2013 Nov 22.

GENE AMPLIFICATION OF THE HISTONE METHYLTRANSFERASE SETDB1 CONTRIBUTES TO HUMAN LUNG TUMORIGENESIS (2014)

M Rodriguez-Paredes, A Martinez de Paz,  L Simó-Riudalbas, et al.

Oncogene​. 2014 May 22;33(21):2807-13.

 doi: 10.1038/onc.2013.239. Epub 2013 Jun 17.

PROMOTER CPG ISLAND HYPERMETHYLATION OF THE DNA REPAIR ENZYME MGMT PREDICTS CLINICAL RESPONSE TO DACARBAZINE IN A PHASE II STUDY FOR METASTATIC COLORECTAL CANCER (2013)

Alessio Amatu, Andrea Sartore-Bianchi, Catia Moutinho, et al.

Clin Cancer Res​. 2013 Apr 15;19(8):2265-72.

 doi: 10.1158/1078-0432.CCR-12-3518. Epub 2013 Feb 19.

CPG ISLAND HYPERMETHYLATION-ASSOCIATED SILENCING OF SMALL NUCLEOLAR RNAS IN HUMAN CANCER (2012)

Humberto J Ferreira, Holger Heyn, Catia Moutinho, et al.

RNA Biol​. 2012 Jun;9(6):881-90.

 doi: 10.4161/rna.19353. Epub 2012 May 23.

DYNAMIC EPIGENETIC REGULATION OF THE MICRORNA-200 FAMILY MEDIATES EPITHELIAL AND MESENCHYMAL TRANSITIONS IN HUMAN TUMORIGENESIS (2012)

V Davalos, C Moutinho, A Villanueva, et al.

Oncogene​. 2012 Apr 19;31(16):2062-74.

 doi: 10.1038/onc.2011.383. Epub 2011 Aug 29.

SMALL MOLECULE ENOXACIN IS A CANCER-SPECIFIC GROWTH INHIBITOR THAT ACTS BY ENHANCING TAR RNA-BINDING PROTEIN 2-MEDIATED MICRORNA PROCESSING (2011)

Sonia Melo, Alberto Villanueva, Catia Moutinho, et al.

Proc Natl Acad Sci U S A​. 2011 Mar 15;108(11):4394-9.

 doi: 10.1073/pnas.1014720108. Epub 2011 Feb 28.

A GENETIC DEFECT IN EXPORTIN-5 TRAPS PRECURSOR MICRORNAS IN THE NUCLEUS OF CANCER CELLS (2010)

Sonia A Melo, Catia Moutinho, Santiago Ropero, et al.

Cancer Cell​. 2010 Oct 19;18(4):303-15.

 doi: 10.1016/j.ccr.2010.09.007.